The wine was originally known as Chateau Milon and it was originally a second wine to Chateau Lafite. That was early in the 1700s and the owner of the estate was Nicolas-Alexandre de Segur. The Casteja family acquired the property and kept it for many years but starting in 1937, the property went through 5 different owner in 5 years. The Rothschild family acquired the property in 1962. At that time, the estate was 110 hectares but only 17 hectares were planted with vines.
Today Chateau Duhart Milon includes 76 hectares of vines planted to 67% Cabernet Sauvignon and 33% Merlot. There is no actual grand building on the estate. The building depicted on the label is known as the "pirate house". Sir Duhart was rumored to be a pirate for Louis XV. The house was in Pauillac Port until the 1950s.